Physiol. Genomics -- Table of Contents (August 2008, 34 [3])

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Reviews:

David J. Adams and Louise van der Weyden: Contemporary approaches for modifying the mouse genome
Physiol. Genomics 34: 225-238, 2008. First published June 17, 2008; doi:10.1152/physiolgenomics.90242.2008 [Abstract] [Full Text] [PDF]

Michael V. G. Latronico, Daniele Catalucci, and Gianluigi Condorelli: MicroRNA and cardiac pathologies
Physiol. Genomics 34: 239-242, 2008. First published June 10, 2008; doi:10.1152/physiolgenomics.90254.2008 [Abstract] [Full Text] [PDF]

Call For Papers: Comparative Genomics:

Silvia Mandillo, Valter Tucci, Sabine M. Hölter, Hamid Meziane, Mumna Al Banchaabouchi, Magdalena Kallnik, Heena V. Lad, Patrick M. Nolan, Abdel-Mouttalib Ouagazzal, Emma L. Coghill, Karin Gale, Elisabetta Golini, Sylvie Jacquot, Wojtek Krezel, Andy Parker, Fabrice Riet, Ilka Schneider, Daniela Marazziti, Johan Auwerx, Steve D. M. Brown, Pierre Chambon, Nadia Rosenthal, Glauco Tocchini-Valentini, and Wolfgang Wurst: Reliability, robustness, and reproducibility in mouse behavioral phenotyping: a cross-laboratory study
Physiol. Genomics 34: 243-255, 2008. First published May 27, 2008; doi:10.1152/physiolgenomics.90207.2008 [Abstract] [Full Text] [PDF]

Daniel Markovich, Alessandro Romano, Carlo Storelli, and Tiziano Verri: Functional and structural characterization of the zebrafish Na⁺-sulfate cotransporter 1 (NaS1) cDNA and gene (slc13a1)
Physiol. Genomics 34: 256-264, 2008. First published June 10, 2008; doi:10.1152/physiolgenomics.90234.2008 [Abstract] [Full Text] [PDF] [Supplemental Figure]

Mark D. Parker, Patrice Bouyer, Christopher M. Daly, and Walter F. Boron: Cloning and characterization of novel human SLC4A8 gene products encoding Na⁺-driven Cl^–/HCO₃^– exchanger variants NDCBE-A, -C, and -D
Physiol. Genomics 34: 265-276, 2008. First published June 24, 2008; doi:10.1152/physiolgenomics.90259.2008 [Abstract] [Full Text] [PDF] [Supplemental Figure]

Research Articles:

Ethan S. Patterson, Russell C. Addis, Michael J. Shamblott, and John D. Gearhart: SOX17 directly activates Zfp202 transcription during in vitro endoderm differentiation
Physiol. Genomics 34: 277-284, 2008. First published June 3, 2008; doi:10.1152/physiolgenomics.90236.2008 [Abstract] [Full Text] [PDF]

Anja Julie Nilsen, Maria A. Landin, Kristin H. Haug, Frode Fonnum, Urs Berger, and Harald Osmundsen: Comparative hepatic gene expression profiling of rats treated with 1H,1H,2H,2H-heptadecafluorodecan-1-ol or with pentadecafluorooctanoic acid
Physiol. Genomics 34: 285-303, 2008. First published June 10, 2008; doi:10.1152/physiolgenomics.00225.2007 [Abstract] [Full Text] [PDF]

Stefka B. Petkova, Rong Yuan, Shirng-Wern Tsaih, William Schott, Derry C. Roopenian, and Beverly Paigen: Genetic influence on immune phenotype revealed strain-specific variations in peripheral blood lineages
Physiol. Genomics 34: 304-314, 2008. First published June 10, 2008; doi:10.1152/physiolgenomics.00185.2007 [Abstract] [Full Text] [PDF]

Yasushi Noguchi, Nahoko Shikata, Yasufumi Furuhata, Takeshi Kimura, and Michio Takahashi: Characterization of dietary protein-dependent amino acid metabolism by linking free amino acids with transcriptional profiles through analysis of correlation
Physiol. Genomics 34: 315-326, 2008. First published June 17, 2008; doi:10.1152/physiolgenomics.00007.2008 [Abstract] [Full Text] [PDF] [Supplemental Figures and Tables]

Sophie Rome, Virginie Lecomte, Emmanuelle Meugnier, Jennifer Rieusset, Cyrille Debard, Vanessa Euthine, Hubert Vidal, and Etienne Lefai: Microarray analyses of SREBP-1a and SREBP-1c target genes identify new regulatory pathways in muscle
Physiol. Genomics 34: 327-337, 2008. First published June 17, 2008; doi:10.1152/physiolgenomics.90211.2008 [Abstract] [Full Text] [PDF] [Supplemental Table]

Michael G. Tordoff, Hongguang Shao, Laura K. Alarcón, Robert F. Margolskee, Bedrich Mosinger, Alexander A. Bachmanov, Danielle R. Reed, and Stuart McCaughey: Involvement of T1R3 in calcium-magnesium taste
Physiol. Genomics 34: 338-348, 2008. First published July 1, 2008; doi:10.1152/physiolgenomics.90200.2008 [Abstract] [Full Text] [PDF]

Cover Caption:

Cover

Cover: Spontaneous null mutation in the actin depolymerizing molecule, destrin (Dstn), leads to changes in the gene expression profile in vivo. The Dstn mutant mouse suffers abnormal actin dynamics as evidenced by accumulation of filamentous actin in the corneal epithelial cells (phalloidin staining, top). The microarray analysis demonstrated a dramatic change in the gene expression profile (right; red and green indicate up- and downregulation of gene expression in the mutant compared with wild-type mice), which is likely involved in the mechanisms causing disease phenotypes including the irregular surface and neovascularization observed in the cornea of Dstn mutant mice (bottom). For details, see Verdoni AM, Aoyama N, Ikeda A, and Ikeda S. Effect of destrin mutations on the gene expression profile in vivo. Physiol. Genomics 34: 9-21, 2008 (first published April 1, 2008); doi: 10.1152/physiolgenomics.00285.2007.